Over two decades of supporting science and research impacting Leonberger health, longevity and breed preservation.
New Research Publication:
Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus
A study made possible by the DNA stored at the Universities of Minnesota and Bern, and your willingness to complete health updates on your dogs. Also with the great help of the pedigree information at the Worldwide Independent Leonberger Database.
Please notice that updates on healthy and long-lived dogs are as important as any other. They become the Control dogs and are necessary for scientific comparison.
"Heritability was determined to be 20%. . . .indicating additional environment factors are having significant impact on the phenotypic variation in Osteosarcoma." This is not the answer, but a link in the chain.
Please also read the summary (below) provided by the researchers. The "What it Means?" section is particularly helpful.
Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus
A study made possible by the DNA stored at the Universities of Minnesota and Bern, and your willingness to complete health updates on your dogs. Also with the great help of the pedigree information at the Worldwide Independent Leonberger Database.
Please notice that updates on healthy and long-lived dogs are as important as any other. They become the Control dogs and are necessary for scientific comparison.
"Heritability was determined to be 20%. . . .indicating additional environment factors are having significant impact on the phenotypic variation in Osteosarcoma." This is not the answer, but a link in the chain.
Please also read the summary (below) provided by the researchers. The "What it Means?" section is particularly helpful.
| Announcement & Summary of OSA publication |
Annual Projects Update from the University of Minnesota:
| umn_progress___plans_december_2021_final.pdf |
